Journal Information
Vol. 15. Issue 4.
Pages 397-398 (July - August 2011)
Share
Share
Download PDF
More article options
Vol. 15. Issue 4.
Pages 397-398 (July - August 2011)
Case report
Open Access
Use of assisted reproductive technology to separate sperm from human immunodeficiency virus infected men resulting in pregnancy among serodiscordant couples
Visits
2779
Alessandro Schuffner1, Ana Paula Lisboa2, Vinicius Bonato da Rosa3, Monica Maria Gomes da Silva4,
Corresponding author
monica.mgomes@gmail.com

Correspondence to: Av. República Argentina, 210/17°, 80240-210 Curitiba, Brazil Phone/fax: +55(41) 3039-5556.
1 Ex-fellow at Jones Institute for Reproductive Medicine, USA; Obstetrician and Gynecologist Specialist; Physician at Conceber, Reproductive Medicine Center, Curitiba, PR, Brazil
2 Obstetrician and Gynecology Specialist; Reproductive Endocrinology Specialist; Physician at Conceber Reproductive Medicine, Curitiba, PR, Brazil
3 Biologist and Embryology Specialist; Biologist at Conceber Reproductive Medicine, Curitiba, PR, Brazil
4 Infectious Diseases Specialist (SBI); Neurology Specialist (ABN); Hospital Nossa Senhora das Graças, Infectious Diseases Department, Curitiba, PR, Brazil
This item has received

Under a Creative Commons license
Article information
Abstract
Bibliography
Download PDF
Statistics
Abstract

Due to HIV care improvement, discordant couples more frequently seek help in order to conceive their own biological child. Besides the advance of antiretroviral therapy, unprotected intercourse is not a complete safe option, carrying a low but still present risk of HIV transmission. We report 10 serodiscordant couples in whom the male partner is HIV positive, submitted to sperm washing and intrauterine insemination. The procedure resulted in four pregnancies and no HIV transmission to mother or child was observed. Techniques of assisted reproduction can help HIV discordant couples to conceive biological offspring and is a safer option than unprotected intercourse.

Keywords:
HIV-1
pregnancy
insemination
artificial reproduction
Full text is only aviable in PDF
References
[1.]
Human immunodeficiency virus and infertility treatment. American Society for Reproductive Medicine, Published by Elsevier Inc. Fertility and Sterility 2010, vol. 94, n. 1, june.
[2.]
A.E. Semprini, P. Levi-Setti, M. Ravizza, et al.
Insemination of HIV-negative women with processed sêmen of HIV-positive partners.
Lancet, 340 (1992), pp. 1317-1319
[3.]
A. Schuffner, R.S. Poletto, T. Placido.
Intrauterine insemination: a realistic alternative in assisted reproduction.
Reprod Clim, 24 (2009), pp. 18-22
[4.]
M.V. Sauer.
Sperm washing techniques address the fertility needs of HIV-seropositive men: a clinical review.
Reprod Biomed Online, 10 (2005), pp. 135-140
[5.]
H.Y. Mark, M.S. Heather, R.L. Mona.
Access to infertility services in Canada for HIV-positive individuals and couples: a crosssectional study.
Reproductive Health, 7 (2010), pp. 7
[6.]
Recomendações para terapia antirretroviral em adultos infectados pelo HIV- 2008 - Suplemento III - Tratamento e prevenção. Brasília, outubro de 2010. Accessed at: http://www.aids.gov.br/publicacao/nota-tecnica-2842010.
[7.]
Implicações éticas quanto às técnicas de reprodução assistida em casais sorodiscordantes para HIV, onde a mulher é soronegativa e o homem é soropositivo”.
Arq Cons Reg Med do PR, 21 (2004), pp. 74-76
[8.]
BHIVA Guidelines Writing Committee.
Guidelines for the management of HIV infection in pregnant women and the prevention of mother-to-child transmission of HIV.
[9.]
L. Townsend, L.G. Johnston, A.J. Flisher, et al.
Effectiveness of respondent-driven sampling to recruit high risk heterosexual men who have multiple female sexual partners: differences in HIV prevalence and sexual risk behaviours measured at two time points.
AIDS Behav, 14 (2010), pp. 1330-1339
[10.]
A.E. Semprini, M. Ravizza, M.L. Muggiasca, et al.
Paternal HIV infection and transfer of HIV from mother to fetus.
Br Med J, 308 (1994), pp. 453
Copyright © 2011. Elsevier Editora Ltda.. All rights reserved
Download PDF
The Brazilian Journal of Infectious Diseases
Article options
Tools