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Vol. 15. Issue 2.
Pages 170-173 (March - April 2011)
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Vol. 15. Issue 2.
Pages 170-173 (March - April 2011)
Brief Comunication
Open Access
Clinical aspects of influenza A (H1N1) in HIV-infected individuals in São Paulo during the pandemic of 2009
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Rosana Del Bianco1, Maria Silvia Biagioni Santos2,
Corresponding author
msbiagioni@gmail.com

Correspondence to: CRT DST AIDS, Rua Santa Cruz 81, Vila Mariana, São Paulo, SP, Brazil. Phone: +55-11-50879887, Fax: +55-11-50879886.
, Maria Clara Gianna Garcia Ribeiro3, Ana Teresa Rodriguez Viso4, Valquíria Carvalho5
1 Master's Degree in Infectology; Director of Inpatient Service, CRT DST AIDS-SES SP
2 Infectologist; Physician of Inpatient Service, CRT DST AIDS-SES SP
3 Sanitarist; Technical Director, CRT DST AIDS-SES SP
4 Infectology; Director of Ambulatory Service, CRT DST AIDS-SES SP
5 Master's Degree in Infectology; Physician of Inpatient Service, CRT DST AIDS-SES SP
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Abstract
Objective

To describe the clinical aspects of H1N1 among HIV coinfected patients seen at a reference center for AIDS treatment in São Paulo, Brazil.

Design

Observational and prospective cohort study.

Methods

Descriptive study of clinical and laboratory investigation of HIV-infected patients with confirmed diagnosis of influenza A (H1N1) in 2009. We analyzed patients monitored in CRT/DST/AIDS, a specialized service for people living with HIV, located in São Paulo, Brazil.

Results

108 individuals presented with symptoms of H1N1 infection at the CRT DST/AIDS in 2009. Eighteen patients (16.7%) had confirmation of the diagnosis of influenza A. Among the confirmed cases, ten (55.6%) were hospitalized and eight (44.4%) were outpatients. Dyspnea was present in nine patients (50%), hemoptysis in three (16%). Six patients (60%) required therapy with supplemental oxygen. All patients had good clinical outcomes and none died.

Conclusions

In our hospital, the symptoms that led patients to seek medical care were similar to the common flu. Hospital admission and the early introduction of antibiotics associated with oseltamivir may have been the cause of the favorable outcome of our cases.

Keywords:
influenza A virus, H1N1 subtype
HIV
acquired immunodeficiency syndrome
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