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Vol. 16. Issue 1.
Pages 92-95 (January - February 2012)
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Vol. 16. Issue 1.
Pages 92-95 (January - February 2012)
Open Access
Autoimmune features caused by dengue fever: a case report
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Denis Leonardo Fontes Jardim
Corresponding author
jardimde@gmail.com

Corresponding author at: Rua Tessália Vieira de Camargo, 126, Cidade Universitária “Zeferino Vaz”, 13083-887, Campinas, SP, Brazil.
, Daniela Miti Lemos Tsukumo, Rodrigo N. Angerami, Marco Antonio de Carvalho Filho, Mário José Abdalla Saad
Department of Internal Medicine, Universidade Estadual de Campinas, Campinas, SP, Brazil
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Abstract

Dengue virus is the most important mosquito-borne viral disease in the world. Co-circulation of the four types of dengue viruses and expansion of dengue epidemic gave rise to infection enhancement and a big expansion of clinical aspects of the disease. Herein we report a case of a 25-year-old white woman with dengue fever and numerous associated autoimmune features. Our patient had proteinuria, an extensive right pleural effusion, a thin pericardial effusion and ascites. She had a low C3 level and positive antinuclear antibody; cryoglobulins were also positive. The numerous autoimmune features of this patient were a diagnostic challenge, since she was a young woman and could be easily mistaken for a rheumatologic patient in a newly open disease. Dengue infection probably was a triggering event causing an abnormal immune response. Therefore, dengue should be suspected in patients with hematological disorders and autoimmune features in endemic regions or those who have travelled to those regions.

Keywords:
Dengue
Autoimmunity
Hematologic diseases
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