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Vol. 15. Issue 5.
Pages 457-461 (September - October 2011)
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Vol. 15. Issue 5.
Pages 457-461 (September - October 2011)
Original article
Open Access
Study of the relationship between socio-demographic characteristics and new influenza A (H1N1)
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Luana Lenzi1, Astrid Wiens1, Mônica Holtz Cavichiolo Grochocki2, Roberto Pontarolo3,
Corresponding author
pontarolo@ufpr.br

Correspondence to: Universidade Federal do Paraná Av. Pref. Lothário Meissner, 632, Jardim Botânico, Curitiba, PR, Brazil 80210-170
1 Pharmacists, Universidade Federal do Paraná (UFPR), Brazil
2 Pharmacist, SESA, PR, Brazil
3 Professor/Adviser, UFPR, Brazil
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Article information
Abstract
Objective

The pandemic of new influenza A (H1N1) has spread rapidly throughout the world, characterized by high transmissibility, but low pathogenicity and virulence. The aim of this study was to understand the pandemic event and available technologies for disease surveillance, prevention, control and management.

Methods

In this retrospective study, we used data from patients in the State of Paraná who had been diagnosed with the disease during the 2009 pandemic. Data were collected from the disease notification form and the study only included patients with confirmed laboratory diagnosis by RT-PCR.

Results

We present the epidemiological profile of 4,740 patients that met the inclusion criteria. The variables age, level of schooling and gestational age were shown to be associated with mortality due to the infection. Gender and race/ethnicity were not associated with the outcome of the infection.

Conclusion

These results underscore the importance of knowing the variables associated with unfavorable outcomes of pandemic influenza infection in order to minimize the health related consequences. Attention should be given to its forms of transmission and to the frailty of certain age groups that have no cross-immunity.

Keywords:
influenza A virus, H1N1 subtype
disease outbreaks
causality
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References
[1.]
E. Carmo, W. Oliveira.
Risco de uma pandemia de influenza pelo vírus A (H1N1). Secretaria de vigilância em Saúde - Ministério da Saúde. Cad.
Saúde Pública, (2009), pp. 1192-1193
[2.]
G. Neumann, T. Noda, Y. Kawaoka.
Emergence and pandemic potential of swine-origin H1N1 influenza virus.
Nature, 459 (2009), pp. 931-939
[3.]
T.S. Ho, S.M. Wang, C.C. Liu.
Historical review of pandemic influenza A in Taiwan.
Pediatr Neonatol, 51 (2009), pp. 83-88
[4.]
P. Palese, M.L. Shaw.
Orthomyxoviridae: the viruses and their replication.
Fields virology,
[5.]
N.M. Bouvier, P. Palese.
The biology of influenza viruses.
Vaccine, 26 (2008), pp. D49-D53
[6.]
T.M. Tumpey, J.A. Belser.
Resurrected pandemic influenza viruses.
Annu Rev Microbiol, 63 (2009), pp. 79-98
[7.]
R. Dutkowski.
Oseltamivir in seasonal influenza: cumulative experience in low- and high-risk patients.
J Antimicrob Chemother, 65 (2010), pp. ii11-ii24
[8.]
L.Y. Chang, S.R. Shih, P.L. Shao, D.T. Huang, L.M. Huang.
Novel swine-origin influenza virus A (H1N1): the first pandemic of the 21st century.
J Formos Med Assoc, 108 (2009), pp. 526-532
[9.]
Centro Brasileiro de Classificação de Doenças. Boletim do Centro Colaborador da OMS para a classificação de doenças em português [internet]. 2002 [cited on Nov 3 2009];23(2). Available at: http://hygeia.fsp.usp.br/∼cbcd/.
[10.]
D.S. Hui, N. Lee, P.K. Chan.
Clinical management of pandemic 2009 influenza A(H1N1) infection.
Chest, 137 (2010), pp. 916-925
[11.]
N. Khazeni, D.M. Bravata, J.E. Holty, et al.
Systematic review: safety and efficacy of extended-duration antiviral chemoprophylaxis against pandemic and seasonal influenza.
Ann Intern Med, 151 (2009), pp. 464-473
[12.]
V. Saraceni.
Outcomes of pandemic influenza (H1N1) 2009 in women of childbearing age, in the city of Rio de Janeiro.
Epidemiol. Serv. Saúde Brasília, 19 (2010), pp. 339-346
[13.]
P. Duarte, A. Venazzi, N. Youssef, et al.
Pacientes com infecção por vírus A (H1N1) admitidos em unidades de terapia intensiva do Estado do Paraná Brasil.
Rev Bras Ter Intensiva, 21 (2009), pp. 231-236
[14.]
E. Montane, J. Lecumberri, M.L. Pedro-Botet.
Influenza A, pregnancy and neuraminidase inhibitors.
Med Clin (Barc), 136 (2011), pp. 688-693
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