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Vol. 15. Issue 6.
Pages 573-577 (November - December 2011)
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Vol. 15. Issue 6.
Pages 573-577 (November - December 2011)
Original article
Open Access
Preventing catheter-associated infections in the Pediatric Intensive Care Unit: Impact of an educational program surveying policies for insertion and care of central venous catheters in a Brazilian teaching hospital
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Marcelo Luiz Abramczyk1,
Corresponding author
mabramczyk@ig.com.br

Correspondence to: Marcelo Luiz Abramczyk Rua Napoleão de Barros, 690/2° – Vila Clementino 04024-062 São Paulo, SP Brazil.
, Werter B. Carvalho2, Eduardo A.S. Medeiros3
1 Infectious Disease Pediatric Department, Universidade Federal de São Paulo (UNIFESP), SP, Brazil
2 Pediatrics Department, Pediatric Intensive Care Unit, Universidade de São Paulo (USP), SP, Brazil
3 Hospital Infection Program, Division of Infectious Diseases, UNIFESP, SP, Brazil
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Article information
Abstract
Objectives

To determine the impact of an educational program on the prevention of central venous catheter-related infections in a Brazilian Pediatric Intensive Care Unit.

Patients and Methods

All patients admitted to the unit between February 2004 and May 2005 were included in the cohort study in a longitudinal assessment. An educational program was developed based on the Centers for Disease Control and Prevention recommendations for prevention of catheter-associated infections and was adapted to local conditions and resources after an initial observational phase. Incidence of catheter-associated infections was measured by means of on-site surveillance.

Results

One hundred eighteen nosocomial infections occurred in 253 patients (46.6 infections per 100 admissions) and in 2,954 patient-days (39.9 infections per 1,000 patient-days). The incidence-density of catheter infections was 31.1 episodes per 1.000 venous central catheter-days before interventions, and 16.5 episodes per 1,000 venous central catheter-days afterwards (relative risk 0.53 [95% CI 0.28–1.01]). Corresponding rates for exit-site catheter infections were 8.0 and 2.5 episodes per 1,000 venous central catheter-days [0.32 (0.07–1.49)], and the rates for bloodstream infections were 23.1 and 13.9 episodes per 1,000 venous central catheter-days, before and after interventions [0.61 (0.32–1.14)].

Conclusion

A prevention strategy targeted at the insertion and maintenance of vascular access can decrease rates of vascular-access infections in pediatric intensive care unit.

Keywords:
catheterization, central venous
Intensive care units
Pediatric disease prevention
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References
[1.]
M.L. Abramczyk, W.B. Carvalho, E.S. Carvalho, et al.
Nosocomial infection in a developing country.
Braz J Infect Dis, 7 (2003), pp. 375-380
[2.]
S.H. Armenian, J. Singh, A.C. Arrieta.
Risk factors for mortality resulting from bloodsstream infections in a pediatric intensive care unit.
Pediatric Infect Dis J, 24 (2005), pp. 309-314
[3.]
P.M. Arnow, E.M. Quimisong, M. Beach.
Consequences of intravascular catheters sepsis.
Clin Infect Dis, 16 (1993), pp. 778-784
[4.]
E. Arruda, I.S. Marinho, E. Rodrigues, et al.
Central venous cathe Ater-related infections in intensive care units.
Braz J Infect Dis, 1 (1997), pp. 182-185
[5.]
S. Ashkenazi, L. Leibovic, Z. Samra, et al.
Risk factors for mortality due to bacteremia and fungemia in childhood.
Clin Infect Dis, 14 (1992), pp. 949-951
[6.]
A.M. Elward, C.S. Hollenbeak, D.K. Warren, et al.
Attributable cost of nosocomial primary bloodstream infection in peditric intensive care unit patients.
Pediatrics, 115 (2005), pp. 868-872
[7.]
M.J. Richards, J.R. Edwards, D.H. Culver, et al.
Nosocomial infections in pediatric intensive care units in the United States.
Pediatrics, 103 (1999), pp. e39
[8.]
M. Urrea, M. Pons, M. Serra, et al.
Prospective incidence study of nosocomial infections in a pediatric intensive care unit.
Pediatric Infect Dis J, 22 (2003), pp. 490-494
[9.]
J.S. Yogorav, A.M. Elward, V.J. Fraser.
Rate, risk factors, and outcome of nosocomial primary bloodstream infection in a pediatric intensive care unit.
Pediatrics, 110 (2002), pp. 481-485
[10.]
V.L. Hashal.
Intravenous catheters and infection.
Surg Clin North Am, 52 (1972), pp. 1407-1417
[11.]
P.C.M. Jong, M.R. Von Meyenfeldt, M. Rouflart, et al.
Complications of central venous catheterization of the subclavian vein: the influence of a parenteral nutrition team.
Acta Anaesth Scand, (1985), pp. 48-52
[12.]
N. Safdar, D.G. Maki.
The pathogenesis of catheter-related bloodstream infection with noncuffed short-term central venous catheters.
Intensive Care Med, 30 (2004), pp. 62-67
[13.]
P. Eggimann, S. Harbarth, M.N. Constantin, et al.
Impact of a prevention strategy target at vascular-access care on incidence of infections acquired in intensive care.
Lancet, 355 (2000), pp. 1864-1868
[14.]
R.D. Lobo, A.S. Levin, L.M.B. Gomes, et al.
Impact of an educational program and policy changes on decreasing catheter-associated bloodstream infections in a medical intensive care unit in Brazil.
Am J Infect Control, 33 (2005), pp. 83-87
[15.]
F. Parras, J. Ena, E. Bouza, et al.
Impact educational program for the prevention of colonization of intravascular catheters.
Infect Control Hosp Epidemiol, 15 (1994), pp. 239-242
[16.]
D.K. Warren, J.E. Zack, M.J. Cox, et al.
An educational intervention to prevent catheter-associated bloodstream infections in a nonteaching, community medical center.
Crit Care Med, 31 (2003), pp. 1959-1963
[17.]
L.A. Mermel, M.F. Barry, R.J. Sheretz, et al.
Guideline for the management of intravascular catheter-related infections.
Infect Control Hosp Epidemiol, 22 (2001), pp. 222-242
[18.]
N.P. O’Grady, M. Alexander, P. Dellinger, et al.
The Healthcare Infection Control Practices Advisory Committee. Guidelines for the prevention of intravascular catheter-related infections.
Infect Control Hosp Epidemiol, 23 (2002), pp. 759-769
[19.]
J.S. Garner, W.R. Jarvis, T.G. Emori, et al.
CDC definitions for nosocomial infections, 1988.
J Infect Control, 16 (1988), pp. 128-140
[20.]
A. Bhutta, C. Gilliam, M. Honeycutt, et al.
Reduction of bloodstream infections associated with catheters in paediatric intensive care unit: stepwise approach.
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