Journal Information
Vol. 14. Issue 6.
Pages 634-636 (November - December 2010)
Share
Share
Download PDF
More article options
Vol. 14. Issue 6.
Pages 634-636 (November - December 2010)
Case report
Open Access
Native valve endocarditis and femoral embolism due to Granulicatella adiacens: a rare case report
Visits
3062
K.E. Vandana1,
Corresponding author
vandanake@gmail.com

Correspondence to: Associate Professor, Dept of Microbiology, Kasturba Medical College, Manipal, Manipal University Karnataka, India-576104.
, C. Mukhopadhyay2, N.R. Rau3, V. Ajith4, P. Rajath5
1 Associate Professor, Department of Microbiology, Kasturba Medical College, Manipal University, Manipal, India
2 Professor, Department of Microbiology, Kasturba Medical College, Manipal University, Manipal, India
3 Professor and Unit Head, Department of Medicine, Kasturba Medical College, Manipal University, Manipal, India
4 Post Graduate Student(MD), Department of Microbiology, Kasturba Medical College, Manipal University, Manipal, India
5 Post Graduate Student(MSc),- Department of Microbiology, Kasturba Medical College, Manipal University, Manipal, India
This item has received

Under a Creative Commons license
Article information
Abstract

The fastidious Gram-positive cocci Granulicatella adiacens, previously known as nutritionally variant streptococci (NVS) are unusual but significant cause of endocarditis due to increased mortality and morbidity. Difficulties in reaching correct bacteriological identification, increased resistance to beta-lactam antibiotics and macrolides and complicated clinical course have contributed to problems in management of cases of infective endocarditis caused by this bacterium. We present the first Indian case of endocarditis with arterial embolus by G. adiacens in an elderly male with no pre-existing cardiac abnormality.

Keywords:
endocarditis
Granulicatella adiacens
femoral embolism
Full text is only aviable in PDF
References
[1.]
W. Wilson, K.A. Taubert, M. Gewitz, et al.
Prevention of Infective Endocarditis Guidelines From the American Heart Association: A Guideline From the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group.
Circulation, 116 (2007), pp. 1736-1754
[2.]
M.J. Tuohy, G.W. Procop, J.A. Washington.
Antimicrobial susceptibility of Abiotrophia adiacens and Abiotrophia defective.
Diagn Microbiol Infect Dis, 38 (2000), pp. 189-191
[3.]
C.H. Liao, L.J. Teng, P.R. Hsueh, et al.
Nutritionally variant streptococcal infections at a University Hospital in Taiwan: disease emergence and high prevalence of beta-lactam and macrolide resistance.
Clin Infect Dis, 38 (2004), pp. 452-455
[4.]
P. Brouqui, D. Raoult.
Endocarditis due to rare and fastidious bacteria.
Clin Microbiol Rev, 14 (2001), pp. 177-207
[5.]
Committee for Clinical Laboratory Standards Institute (Formerly National Committee for Clinical Laboratory Standards). 2005. Performance standards for antimicrobial disk susceptibility testing, fifteenth informational supplement. Approved standard M2-A8. National Committee for Clinical Laboratory Standards, Wayne, Pa.
[6.]
J.P. Casalta, G. Habib, B. La Scola, M. Drancourt, T. Caus, D. Raoult.
Molecular diagnosis of Granulicatella elegans on the cardiac valve of a patient with culture-negative endocarditis.
J Clin Microbiol, 40 (2002), pp. 1845-1847
[7.]
M.D. Collins, P.A. Lawson.
The genus Abiotrophia (Kawamura et al.) Is not monophyletic: proposal of Granulicatella gen. November, Granulicatella adiacens comb. November, Granulicatella elegans comb. And November Granulicatella balaenopterae comb.
November Int J Syst Evol Microbiol, 50 (2000), pp. 365-369
[8.]
L. Senn, J.M. Entenza, G. Greub, et al.
Bloodstream and endovascular infections due to Abiotrophia defective and Granulicatella species.
BMC Infect Dis, 20 (2006), pp. 9
[9.]
Y. Ohara-Nemoto, K. Kishi, M. Sathe, et al.
Infective endocarditis caused by Granulicatella elegans originating in the oral cavity.
J Clin Microbiol, 43 (2005), pp. 1405-1407
[10.]
V. Ozenci, D. Salaj, H. Fang, Westling K..
Relapsing endocarditis due to Granulicatella adiacens.
Int J Antimicrob Agents, 33 (2009), pp. S47
[11.]
A. Perkins, S. Osorio, M. Serrano, et al.
A case of endocarditis due to Granulicatella adiacens.
Clin Microbiol Infect, 9 (2003), pp. 576-577
[12.]
P.C. Woo, A.M. Fung, S.K. Lau, et al.
Granulicatella adiacens and Abiotrophia defective bacteraemia characterized by 16S rRNA gene sequencing.
J Med Microbiol, 52 (2003), pp. 137-140
[13.]
S.H. Chang, C.C. Lee, S.Y. Chen, I.C. Chen, M.R. Hsieh, S.C. Chen.
Infectious intracranial aneurysms caused by Granulicatella adiacens.
Diagn Microbiol Infect Dis, 60 (2008), pp. 201-204
[14.]
O. Rosenthal, A. Woywodt, P. Kirschner, H. Haller.
Vertebral osteomyelitis and endocarditis of a pacemaker lead due to Granulicatella (Abiotrophia) adiacens.
Infection, 30 (2002), pp. 317-319
[15.]
A. Eng, J. Chen, T. Katsivas.
Prosthetic valve endocarditis from Granulicatella adiacens (nutritionally variant streptococci).
J Infect, 51 (2005), pp. 125-129
Copyright © 2010. Elsevier Editora Ltda.. All rights reserved
Download PDF
The Brazilian Journal of Infectious Diseases
Article options
Tools