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Vol. 15. Issue 6.
Pages 601-606 (November - December 2011)
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Vol. 15. Issue 6.
Pages 601-606 (November - December 2011)
Original article
Open Access
Immune reconstitution inflammatory syndrome associated with pulmonary sarcoidosis in an HIV-infected patient: an immunohistochemical study
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Érique José Peixoto de Miranda1,*, Olavo Henrique Munhoz Leite2, Maria Irma Seixas Duarte3
1 Resident Physician, Department of Infectious Diseases, Medical School, Universidade de São Paulo (USP), SP, Brazil
2 Department of Infectious Diseases, Medical School, USP, Brazil
3 Department of Pathology, Medical School, USP, Brazil
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Article information
Abstract

Sarcoidosis has been rarely described in literature as a cause of interstitial pulmonary disease associated with AIDS. This study reports a case of immune reconstitution inflammatory syndrome associated with pulmonary sarcoidosis in a patient with a history of previous pulmonary tuberculosis concomitant with HIV infection. Results of the immunohistochemical study of samples from the resected right lower lobe are described. Pathological findings suggest a role of Th1, Th2 and Th17 response in IRIS associated sarcoidosis.

Keywords:
acquired immunodeficiency syndrome
sarcoidosis, pulmonary
immune reconstitution inflammatory syndrome
immunohistochemistry
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