Fulminant pancytopenia due to cytomegalovirus infection in an immunocompetent adult

Koukoulaki, Maria; Ifanti, Georgia; Grispou, Eirini; Papastamopoulos, Vassilios; Chroni, Georgia; Diamantopoulos, Emmanouil; Skoutelis, Athanasios

doi:10.1016/S1413-8670(10)70034-9

The Brazilian Journal of Infectious Diseases

ISSN: 1413-8670

The Brazilian Journal of Infectious Diseases is the official publication of the Brazilian Society of Infectious Diseases (SBI). It aims to publish relevant articles in the broadest sense on all aspects of microbiology, infectious diseases and immune response to infectious agents.
The BJID is a bimonthly publication and one of the most influential journals in its field in Brazil and Latin America with a high impact factor. Since its inception it has garnered a growing share of the publishing market.

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A case of severe and irreversible pancytopenia secondary to acute primary cytomegalovirus infection in an immunocompetent woman is described. The patient presented with thrombocytopenia, lymphopenia, anemia, and abnormal liver function tests. Treatment with corticosteroids and intravenous immunoglobulin was ineffective in reconstituting hemopoiesis. The patient developed severe sepsis and eventually expired.

Keywords:

cytomegalovirus

pancytopenia

immunocompetent

fulminant

irreversible

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