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Vol. 15. Issue 2.
Pages 178-180 (March - April 2011)
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Vol. 15. Issue 2.
Pages 178-180 (March - April 2011)
Case report
Open Access
Fatal meningococcal meningitis in a HIV-infected patient caused by serogroup C Neisseria meningitidis belonging to the non-hypervirulent clonal complex ST-60 (cc60)
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Claudia Ferreira de Andrade1, Denise Cotrim da Cunha2, Veronica Cavalcanti3, Ivano de Filippis4,
Corresponding author
ivano.defilippis@incqs.fiocruz.br

Correspondence to: Instituto Nacional de Controle de Qualidade em Saúde, Fundação Oswaldo Cruz Av. Brasil, 4365, Rio de Janeiro, Brazil 21045-900. Phone: +55-21-3865-5236, Fax: +55-21-2290-0915.
1 Laboratory Technician, INCQS/FIOCRUZ, Rio de Janeiro, Brazil
2 Physician, Hospital Lourenço Jorge, Rio de Janeiro, Brazil
3 Clinical Pathology Technician, Hospital Lourenço Jorge, Rio de Janeiro, Brazil
4 Senior Technologist, INCQS/FIOCRUZ, Rio de Janeiro, Brazil
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Abstract

Meningococcal strains belonging to clonal complex cc60 are not associated with hypervirulent lineages and were never reported as causing disease in Latin American countries. This is the first report of a fatal meningitis case caused by a cc60 clonal complex meningococcus in Brazil. Despite the immune-compromised state of the patient, the fatal outcome here described shows the potential pathogenic behavior of strains belonging to this clonal complex and how compromised hosts can be susceptible to meningococcal infections even if the strain is not particularly invasive.

Keywords:
meningitis, meningococcal
meningococcal infections
Neisseria meningitidis
serogroup C
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