TY - JOUR T1 - Two cases of neural tube defects with dolutegravir use at conception in south Brazil JO - The Brazilian Journal of Infectious Diseases T2 - AU - Kreitchmann,Regis AU - Oliveira,Fernando Rocha de AU - Sprinz,Eduardo SN - 14138670 M3 - 10.1016/j.bjid.2021.101572 DO - 10.1016/j.bjid.2021.101572 UR - https://bjid.org.br/en-two-cases-neural-tube-defects-articulo-S1413867021000416 AB - Dolutegravir (DTG) is amongst the most prescribed antiretrovirals worldwide and is recommended as first line regimen in most HIV treatment guidelines. Its use, although infrequently, had been associated to an increased chance of neural tube defects (NTD) in Botswana, Africa. Herein we describe two cases of NTD in women who conceived while taking DTG as part of their antiretroviral treatment in the city of Porto Alegre, Brazil. ER -