The Brazilian Journal of Infectious Diseases The Brazilian Journal of Infectious Diseases
Braz J Infect Dis 2017;21:180-4 - Vol. 21 Num.2 DOI: 10.1016/j.bjid.2016.10.006
Brief communication
Prevalence of Trypanosoma cruzi/HIV coinfection in southern Brazil
Dulce Staufferta,b, Mariangela Freitas da Silveiraa,c, Marília Arndt Mesenburgc, Adriane Brod Mantaa, Alessandra da Silva Dutrab, Guilherme Lucas de Oliveira Biccaa, Marcos Marreiro Villelab,,
a Universidade Federal de Pelotas, Faculdade de Medicina, Departamento de Saúde Materno-Infantil, Pelotas, RS, Brazil
b Universidade Federal de Pelotas, Instituto de Biologia, Programa de Pós-graduação em Parasitologia, Pelotas, RS, Brazil
c Universidade Federal de Pelotas, Programa Pós-graduação em Epidemiologia, Pelotas, RS, Brazil
Received 13 July 2016, Accepted 13 October 2016
Abstract

Chagas disease reactivation has been a defining condition for acquired immune deficiency syndrome in Brazil for individuals coinfected with Trypanosoma cruzi and HIV since 2004. Although the first coinfection case was reported in the 1980s, its prevalence has not been firmly established. In order to know coinfection prevalence, a cross-sectional study of 200 HIV patients was performed between January and July 2013 in the city of Pelotas, in southern Rio Grande do Sul, an endemic area for Chagas disease. Ten subjects were found positive for T. cruzi infection by chemiluminescence microparticle immunoassay and indirect immunofluorescence. The survey showed 5% coinfection prevalence among HIV patients (95% CI: 2.0–8.0), which was 3.8 times as high as that estimated by the Ministry of Health of Brazil. Six individuals had a viral load higher than 100,000copies per μL, a statistically significant difference for T. cruzi presence. These findings highlight the importance of screening HIV patients from Chagas disease endemic areas.

Keywords
Chagas disease, Trypanosoma cruzi, AIDS
Braz J Infect Dis 2017;21:180-4 - Vol. 21 Num.2 DOI: 10.1016/j.bjid.2016.10.006