TY - JOUR T1 - Prevalence and risk factors for human papillomavirus infection among Chinese ethnic women in southern of Yunnan, China JO - The Brazilian Journal of Infectious Diseases T2 - AU - Baloch,Zulqarnain AU - Yasmeen,Nafeesa AU - Li,Yuanyue AU - Ma,Ke AU - Wu,Xiaomei AU - Yang,Shi-hua AU - Xia,Xueshan SN - 14138670 M3 - 10.1016/j.bjid.2017.01.009 DO - 10.1016/j.bjid.2017.01.009 UR - https://bjid.org.br/en-prevalence-risk-factors-for-human-articulo-S141386701630633X AB - BackgroundDai is a major Chinese ethnic minority group residing in rural areas of the southern part of Yunnan. However, no data exist on the Human Papillomavirus (HPV) prevalence and genotype distribution among Dai women. MethodA total of 793 participants (Dai=324, Han=251, other ethnic=218) were included in this study. PCR was performed to detect the HPV-positive samples, and genotyping was performed with an HPV Geno-Array. ResultThe overall HPV prevalence was very low among Dai women compared to the others. The prevalence of high-risk-HPV infections was significantly higher (p=0.001) among other ethnic women (22.0%) than that among Han (13.1%) and Dai women (7.1%). The overall HPV, high-risk-HPV, single and multiple infection prevalence among rural women were 12.9%, 12.1%, 12.3%, and 0.5%, respectively. HPV-16 (5.5%) was shown to be the most prevalent genotype, followed by HPV-52 (2.6%) and HPV-58 (2.4%). Urban women had relatively higher rates of overall HPV (16.0%), high-risk-HPV (14.1%), single genotype (11.9%), and multiple genotype (4.1%) infections. In urban women, HPV-52 (3.6%) was the most prevalent genotype, followed by HPV-39 (2.7%) and HPV-16 (1.2%). In the urban area, HPV prevalence was highest in women aged <29 years, but declined with increasing age. However, in rural women, the highest HPV prevalence was observed among women at older age (>50 years). Education and smoking habit were significantly associated with HPV infection among both rural and urban area women (p<0.001). ConclusionThe prevalence and genotype distribution of HPV varied among ethnic women in urban and rural area of Yunnan Province. ER -